Disorganization can make you "crazy". Always losing things, working from a messy desk and feeling bad about your messy house will take its toll on your sanity. Spend at least one day a month simply organizing your life. Or the next time you can't find something, instead of wasting time feeling frustrated and looking everywhere for it, just start cleaning and organizing your space. You'll probably spend about the same amount of time clearing up as you would have wasted searching for the lost item. And you'll almost always find the lost item in the process.
Remember, all change begin with awareness of what it is you want to change. When you decide what it is you want to change, or the new habit you want to add in, start small. Make one change at a time and practice it for weeks, if not months, before adding in additional layers of change. That way, you will ensure your eventual success. And even if you experience a setback, remember that setbacks are a part of the process. Get right back on that bucking horse named CHANGE and keep riding her until you reach the finish line where you will not be the least bit tempted to go back to your old ways.